U.S. Route 421 (also U.S. Highway 421, US 421) is a diagonal northwest–southeast United States Numbered Highway in the states of North Carolina, Tennessee, Virginia, Kentucky, and Indiana. The highway runs for 941 miles (1,514 km) from Fort Fisher, North Carolina, to US 20 in Michigan City, Indiana.

In the U.S. state of North Carolina, US 421 travels 328 miles (528 km) from its southern terminus at Fort Fisher to the Tennessee state line near the community of Zionville, North Carolina. US 421 traverses the state from east to west travelling from the coastal plains to Appalachian Mountains.

U.S. Route 421 traverses approximately 328 miles (528 km) across North Carolina; from Fort Fisher, on a peninsula between the Atlantic and Cape Fear River, to the Tennessee state line near the community of Zionville.

U.S. Route 421 (US 421) enters Indiana from Kentucky, proceeding northwest to Indianapolis, joining Interstate 465, and then continuing northwest to Michigan City. US 421 winds through the southern part of Indiana as it runs from Madison, in the southeastern part of the state, to

Oct 23, 2024 · In the U.S. state of North Carolina, US 421 travels 328 miles (528 km) from its southern terminus at Fort Fisher to the Tennessee state line near the community of Zionville, North Carolina. US 421 traverses the state from east to west travelling from the coastal plains to Appalachian Mountains.

Heading toward Deep Gap on US 421, New River peeks out from the trees as the Blue Ridge Mountains come into the foreground for enviable views full of hardwood and mixed forest that in the chilly air of autumn burst with pops of red and yellow along the mountainsides.

Sep 23, 2024 · US route 421 has endpoints in Michigan City (Indiana) and Ft. Fisher (North Carolina), with historic termini in Bristol, Cumberland Gap, Wilmington, Greensboro, and Boone. US Ends .com Home

Sep 11, 2018 · U.S. 421 traverses the state of North Carolina from the Blue Ridge Mountains and Boone east to the Piedmont Triad and the port city of Wilmington.

As the US 421 Scenic Byway travels through the Blue Ridge Mountains, it offers sweeping views of the valleys, woodlands, and mountains between the towns of Deep Gap and Boone. It also runs near the home of multiple Grammy Award winner and cultural icon Doc Watson.

The U.S. 421 Scenic Byway travels through Watauga County’s portion of the Blue Ridge Mountains. The byway offers sweeping views of the valleys, woodlands, and mountains between Deep Gap and Boone. The byway begins on U.S. 421 North at …