Two lanes of US-421 near Cloverdale Avenue in Winston-Salem are closed due to a non-vehicle fire. The lanes are closed past Exit 234. Sign up for our Newsletters Top Stories: Get the latest news ...

A serious three-vehicle crash on Wednesday shut down U.S. Highway 421 in Lillington. Before 1 p.m., Sky 5 flew over the scene near Willie Cameron Road. U.S. 421 was closed in both directions.

A Lillington woman was killed in a head-on crash on US 421 in Lee County on Wednesday. A Lillington woman died in a crash on US 421 in Lee County on Wednesday. North Carolina State Highway Patrol ...