Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...
A European research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating Ch ...
As a first-line therapy, DS-1062/Keytruda had an ORR ... Most EGFR-mutated NSCLCs show some level of HER3 expression, but for now there are no HER3 directed therapies approved for NSCLC or any ...
The approval means Kelun has brought its TROP2 ADC to market ahead of AstraZeneca and Daiichi Sankyo's datopotamab deruxtecan (Dato-DXd), whose FDA filing in non-small cell lung cancer (NSCLC ...
CHENGDU, China I February 12, 2025 I At the American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium 2025, to be held in San Francisco, USA, from Feb. 13-15, 2025, Sichuan ...
Background Endometrial cancer is the most common gynecologic malignancy in developed countries. Trop-2 is a glycoprotein involved in cellular signal transduction and is differentially ...
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York. 3Department of Radiology, Weill Cornell Medical College, New York, New York. *Corresponding Author: Jason S. Lewis ...
Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...
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