Medscape10d
Trop-2 Protein Overexpression is an Independent Marker for Predicting Disease Recurrence in Endometrioid Endometrial Carcinoma
Background Endometrial cancer is the most common gynecologic malignancy in developed countries. Trop-2 is a glycoprotein involved in cellular signal transduction and is differentially ...
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Figure 4 (IMAGE)
Increased Trop-2 expression in MDA-MB-231 tumors overcomes resistance to SG but not irinotecan. NCr athymic nu/nu mice were injected s.c. with either MDA-MB-231 parental cells (parental), MDA-MB ...
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GILD's Trodelvy Gets Second Breakthrough Therapy Tag for Lung Cancer
as well as tumors with high Trop-2 expression. These include SCLC, where the drug showed promise in the TROPiCS-03 study, and first-line metastatic non-small cell lung cancer, demonstrated in the ...
Medscape22d
Trop-2 Protein Overexpression is an Independent Marker for Predicting Disease Recurrence in Endometrioid Endometrial Carcinoma
This study corroborates previous reports on the importance of Trop-2 expression in human tumors to stratify biologically aggressive disease variants. Importantly, because Trop-2 overexpression may ...