One recent novel addition to the treatment toolbox for TRD is esketamine nasal spray (Spravato), which has been ... Toronto, Ontario, Canada, said he’s seen the benefits of the glutamate ...

Recently, President Donald Trump said that U.S. tariffs on imports from Canada and Mexico “will go forward” when ... FDA approval of a supplemental New Drug Application (sNDA) for SPRAVATO ® ...

Spravato (esketamine) has possible interactions with alcohol, some other drugs, and certain supplements. Examples include Adderall and benzodiazepines such as clonazepam (Klonopin). Talk with your ...

Canadians’ views on becoming the 51st state: Trump falsely claimed to reporters in January that “the people of Canada like” his idea of Canada joining the US. In fact, poll after poll has ...

President Donald Trump correctly noted Friday, as he has before, that Canada has tariffs above 200% on dairy products imported from the US. But Trump again failed to mention a critical fact.

LA MALBAIE, Canada—Top diplomats from the world’s industrial democracies gathered here with an extraordinary question looming: How to respond to President Trump’s threats to economically ...

Johnson & Johnson has priced its new Spravato nasal spray for treatment-resistant depression (TRD) too high to offer value for money, says a US cost-effectiveness body. The Institute for Clinical ...

Spravato has been approved since 2019 for TRD, with its label extended the following year as a rescue therapy for adults with major depressive disorder (MDD) who were at risk of self-harm or suicide.

In January, 2025, J&J’s nasal spray Spravato secured a label expansion from the FDA for use as a single agent in adults with major depressive disorder (who were not responsive to two oral ...