Scleroderma is an autoimmune condition that primarily causes thickening of your skin. For some people, bladder or urinary problems may also develop. Some treatments for scleroderma may also cause ...

The cause of this abnormal immune response is not yet known ... Environmental factors that may trigger the onset of CREST syndrome and scleroderma-like disorders include: Viral infections, including ...

was the most severe complication of scleroderma and the most frequent cause of death. SRC is defined as a new onset of extremely high, arterial blood pressure or "rapidly progressive oliguric ...

The exact cause of scleroderma remains unknown, but it is recognized as having an autoimmune basis, with the most likely ...

The underlying cause is unknown. There are different forms of scleroderma, with some types affecting specific parts of the body and others being systemic. The mildest forms of localised ...

Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating ...

Scleroderma is a rare disease in which a person's immune system ... and digestive tract—is replaced with scar tissue. This change causes the tissues to become stiff and the muscles to not work as well ...

have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) and inflammation.

These patients with scleroderma should be carefully evaluated for non-scleroderma causes of kidney disease.

in sera from patients with systemic sclerosis (scleroderma). The authors performed a series of experiments that confirmed that these antibodies recognized and activated native PDGFR on fibroblasts.