Predictive biomarkers of immunotherapy response are critical for clinical practice. In this study, baseline plasma sCD27 was ...
Findings on golidocitinib for patients with non-small cell lung cancer whose disease has progressed on anti-PD-1 therapy will ...
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Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cellsA new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 ...
MHC-I upregulation by macbecin II in the solid tumors potentiates the effect of active immunotherapy
Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...
Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...
The first patient has been dosed in the phase 3 TACTI-004 trial evaluating efti with Keytruda and chemotherapy for advanced ...
In addition, SV-BR-1_GM therapy appeared to upregulate PD-L1 expression in ... from the blood of the cancer patient. CAMLs are macrophages that have engulfed tumor cells from tumor site.
Actinium Pharmaceuticals, Inc. (NYSE AMERICAN: ATNM) (Actinium or the Company), a pioneer in the development of targeted radiotherapies, today announced a clinical program comprising of trials ...
The first patient has been treated in a phase 1/ ... s PD-1 inhibitor Keytruda (pembrolizumab), a widely-used treatment for various cancers, including melanoma and non-small cell lung cancer ...
Immune checkpoint inhibitors like PD-1 inhibitors are available to treat dozens of cancer types ... immunotherapy-activated immune cells share a common gene expression profile.
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