Recent studies show that Musashi-2 (MSI2), a molecule that binds RNA, increases proliferation of normal and ... renewing precursor cells that are tightly regulated. These hematopoietic stem ...

Zaltenibart’s conveniently infrequent dosing together with its ability to inhibit both intravascular and extravascular hemolysis provide a meaningful differentiation from the other PNH therapies.

Omeros Corporation today reported that clinical trial site activation for enrollment is underway for the company's Phase 3 program evaluating zaltenibart in paroxysmal nocturnal hemoglobinuria (PNH).

Significant technological progress has been made in identifying hematological stress inducers and treating hematopoietic diseases ... affecting the stem cell niche maintenance, self-renew, and ...

The generation of red blood cells (RBCs) occurs in the bone marrow hematopoietic compartments. The precursors of erythrocytes are erythroblasts, which are produced by differentiation ... in 10%–20% of ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

A study led by Prof. Liu Feng from the Institute of Zoology of the Chinese Academy of Sciences has identified a crucial role ...

Minor histocompatibility antigens selectively expressed on hematopoietic cells cause a graft-versus-leukemia effect, but not graft-versus-host disease; antigens expressed on hematopoietic cells ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Mar. 11, 2025 — Researchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences ...