Microscale thermophoresis (MST) has emerged as a cutting-edge analytical technique, offering researchers robust and efficient solutions for studying biomolecular interactions. From drug discovery to ...

The assay was most recently used to show that defects in a multimeric protein complex that coats transport vesicles (COPII coat) are responsible for at least two rare diseases. Though ...

Structural determination of both full-length proteins and multimeric ubiquitin-mediated complexes remains one of the biggest challenges. At present, there is no single structure of any protein ...