An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of ...

Other myopathy conditions, such as Duchenne muscular dystrophy ... The finding via GSEA analysis that metabolic functions, especially those related to mitochondrial function, are downregulated, is ...

Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle ...

Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune inflammatory disorders characterised by symmetrical skeletal muscle weakness and accelerated fatigue also in the early ...

Two new papers describe a significant advance in understanding the complex functions of the metabolic network. Two papers published today in the journal Nature describe a significant advance in ...

Here we characterized the action of amphiphysin (BIN1) and dynamin (DNM2), two main regulators of membrane remodeling mutated in congenital myopathies. We found their interplay is necessary for ...

We show here in mature adipocytes, ribosomal transcription can be acutely regulated in response to metabolic challenges. This acute response is mediated by PTRF (polymerase I transcription and release ...