The first intimation is given in Scene 2, Act. IV. Here Lady Macduff talking of her husband says: His flight was madness. . . . for the poor wren The most diminutive of bird, will fight ...

The London Standard has reported this was due to a mid-show switch-up in the cast, with understudy Gemma Laurie stepping in as Lady Macduff after regular performer Rona Morison lost her voice.

Family Macduff puts his loyalty to his king and country before his family. He leaves his family and joins Malcolm in England. His wife, Lady Macduff, is angry and upset that he has left them behind.