UD researchers discover that differences in gene expression in fat could be the key to targeted obesity treatment. According ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

This important study offers a molecular characterization of neurons and glia in the adult nervous system of the fruit fly Drosophila melanogaster. The study focuses on the progeny of a specific set of ...

An Italian research team has found that radicchio seedlings grown in a lab-scale greenhouse with a perovskite solar PV roof ...

Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding ocular disorder with an unknown etiology. Lack of targeted effective drugs, inadequate disease prognosis, and high relapse ...

Resilience relies on the brain’s ability to regulate emotion, adapt, and recover. Myelin plasticity helps speed up and stabilize resilient brain responses. Genes like FKBP5 and BDNF affect how people ...

bMIND is a Bayesian deconvolution method to integrate bulk and scRNA-seq data. With a prior derived from scRNA-seq data, we estimate cell-type-specific (CTS) expression from bulk tissue expression via ...

Introduction COPD is a chronic, progressive, inflammatory disease of the lungs and the third leading cause of death worldwide. The current knowledge of the pathophysiology of COPD is limited and novel ...

Although it is well-known that sex and age are important factors regulating endothelial cell (EC) function, the impact of sex and age on the gene expression of ECs has not been systematically analyzed ...

A question of fundamental biological significance is to what extent the expression of a subset of genes can be used to recover the full transcriptome, with important implications for biological ...