This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

Mouse models for hemophilia A are commonly generated by factor VIII (FVIII) knockout, however, these mice rapidly develop anti-FVIII antibodies during repetitive FVIII administration. To overcome this ...

In related news, other scientists recently reported that phospho-tau isoforms in the CSF mirror protofibrillar forms of tau, ...

A former council pest control officer who is in the fourth year of running his own business says that Plymouth continues to ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

A research team from Osaka University investigates the impact of antioxidant enzymes on specific cell types and their role in ...

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of ...

A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Alpha-GPC, a choline-rich supplement, enhances brain health by increasing acetylcholine, with potential applications in ...