Illuminating brain circuits in the axolotl: Viral vectors enable dynamic brain mapping
The axolotl (Ambystoma mexicanum) has extraordinary regenerative abilities—the salamander can regrow lost limbs and repair ...
Too Old to Operate15d
Impact of PROC Variant C101F on Protein C Stability
The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I protein C deficiency,” published in the February 2025 issue of the ...
Associated Press25d
Researchers link a gene to the emergence of spoken language
A new study links a particular gene to the ancient origins of spoken language, proposing that a protein variant found only in humans may have helped us communicate in a novel way. Speech allowed us to ...
Nature25d
A human gene makes mice squeak differently — did it contribute to language?
Mice carrying a gene variant present in nearly every human on Earth — but not in extinct relatives including Neanderthals — produce more-complex chirps than normal rodents do 1. The finding ...
Frontiers3y
Scalable Dual-Fluorescence Assay for Functional Interpretation of HNF-4α Missense Variants
Aim: The study aimed to develop a scalable dual-fluorescence assay in cells to enable the functional interpretation of HNF-4α missense variants identified in exome sequencing, which can be used to ...
Frontiers4y
Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters
Both constructs also contained an IRES GFP downstream of the Rbfox1 coding sequence to detect ... All spliced Rbfox1 transcript variants that were detected by Iso-Seq in the P0 cerebral cortex are ...