This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

This study presents solid evidence for distinct neurotransmitter release modalities between two subclasses of dopaminergic neurons in the olfactory bulb, highlighting an important finding that ...

A team led by the Institute for Bioengineering of Catalonia (IBEC) and the Hospital del Mar Research Institute has developed ...

There, the researchers observed that the fish DNA elements now activated the green fluorescent protein in the developing transgenic mice’s outer ear, reinforcing the idea that the same ...

Joseph Arboleda-Velasquez of Harvard Medical School praised the results. “Ye’s group has now provided compelling evidence showing increased binding affinity of ApoE3 Christchurch for tau and its ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

The effects of radiotherapy on lymphangiogenesis in wound healing were determined using utilising an in vivo tail model in Prox-1/GFP mice. The tail model allowed interrogation of lymphatic ...

Full-length cDNA encoding human MYBL2 was synthesized and inserted into the pCDH-CMV-GFP-T2A-Puro vector (Addgene ... v.4.0.3. Six- to eight-week-old male BALB/c-nu/nu mice were purchased from ...

Parallel studies in mice confirm the arthritogenic potential of NFIL3-deficiency ... N-terminally FLAG-tagged human NFIL3-T2A-GFP (WT or carrying the M170I mutation) was expressed transiently from a ...

Organoids were cultured from healthy donor iPSC sources and differentiated using the human iPSC-derived Cerebral Organoid ...