This important study employed multiple orthogonal techniques and tissue samples to investigate the interaction between the NRL transcription factor and RNA-binding proteins in the retina. The findings ...
NRL interacts with RNA-binding proteins. A) Summary of experimental strategies used to identify NRL interactors. An AlphaFold-predicted model of human NRL is shown, with protein domains highlighted.
Vision is one of the most crucial human senses, yet more than 300 million people worldwide are at risk of vision loss due to ...
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The lack of regeneration in the human central ...
Background To examine the normative profile and determinants of retinal nerve fibre layer (RNFL) symmetry in a non-glaucoma, multiethnic Asian population. Methods Chinese, Malay and Indian adults aged ...
The CRISPR/Cas systems in prokaryotes such as bacteria and archaea are the adaptive immune system to prevent infection from viruses, phages, or other foreign substances. When viruses or phages first ...
4 Department of Neurology, Strasbourg University and Clinical Investigation Center, Strasbourg Hospital, France Correspondence to Dr Jerome de Seze, Department of Neurology and Clinical Investigation ...
Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, ...