Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

For a time, however, it appeared that fluorescent protein engineering had hit a 'yellow' wall in efforts to red-shift fluorescence emission. Fortuitously, this barrier had already been surmounted ...

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, ...

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease ...

Scientists need sharp tools to peek into the tiny world of biology, and fluorescence microscopy has been a game-changer ...

Bio-conjugation techniques utilizing proteins, such as attaching fluorescent markers to identify cancer cells, are actively ...

1 This was the first example of a light-activated protein, which they called a photoprotein. I wanted to have a tool like this. I thought this would be wonderful. —Martin Chalfie, Columbia University ...

A research team has developed an innovative technique that enables precise modification of specific proteins within complex ...

A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...

Artificial cells using riboswitch-gene fusion in liposomes produce fluorescent proteins when detecting specific targets.