Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

Ten years of substantial work by Nathalie Labrecque's team at the Montreal Clinical Research Institute (IRCM) and the ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative ...

Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.