How a critical enzyme keeps potentially dangerous genes in check
You may have heard of the fantastic-sounding "dark side of the genome." This poorly studied fraction of DNA, known as ...
Duchenne muscular dystrophy's impact on the brain may be reversible
New research led by the University of Portsmouth has revealed how Duchenne muscular dystrophy (DMD), best known for causing ...
STAT3d
At meeting on guardrails for gene editing of human embryos, some call for a dead end
At meeting on human embryo editing, CRISPR pioneer says science is a long way from knowing if germline DNA can be safely ...
AHA/ASA Journals6d
XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity
BACKGROUND: Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes ...
eLife7d
Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability
The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...
eLife13d
Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...
gbnews15d
Gene Hackman's home was in 'shocking' state before his death alongside wife as tragic update about dog confirmed
Gene Hackman and his wife Betsy Arakawa's home was described as 'a mess' Getty Following their deaths, Gene's daughter Leslie paid tribute to Betsy for "keeping him alive" and said they had a ...
BioSpace20d
Beam’s Gene Editor Achieves ‘First Ever’ Genetic Correction in AATD
In a note to investors on Monday, William Blair analysts said these initial data for BEAM-302 “validates the safety and efficacy” of Beam’s lipid nanoparticle and in vivo base editing platform, adding ...
E!21d
Gene Hackman Death Investigation: Every Tragic Twist After Actor, Wife Betsy Arakawa Were Found Dead
Gene Hackman was an acting legend, and his death at 95 prompted the expected outpouring of tributes and career appraisals, including a special mention from his Unforgiven costar Morgan Freeman ...
The Mirror21d
Gene Hackman autopsy uncovers heartbreaking detail about starving star's final struggle
Double Oscar-winning actor Gene Hackman's tragic final moments have been revealed after he died at least a week after his beloved wife, Betsy Arakawa. Gene, 95, died in the mud room of his Santa ...
The New York Times21d
Mutated DNA Restored to Normal in Gene Therapy Advance
By Gina Kolata Researchers have corrected a disease-causing gene mutation with a single infusion carrying a treatment that precisely targeted the errant gene. This was the first time a mutated ...
Fox News22d
Gene Hackman death: Alzheimer's impact on actor in days after wife's death
Gene Hackman may not have realized his wife, Betsy Arakawa Hackman, was dead during his final weeks due to his advanced Alzheimer’s, according to forensic pathologist Dr. Michael Baden.