Duchenne muscular dystrophy's impact on the brain may be reversible
New research led by the University of Portsmouth has revealed how Duchenne muscular dystrophy (DMD), best known for causing ...
STAT19h
At meeting on guardrails for gene editing of human embryos, some call for a dead end
At meeting on human embryo editing, CRISPR pioneer says science is a long way from knowing if germline DNA can be safely ...
Gene editing with adeno-associated virus vector offers hope for hereditary deafness
An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...
eLife5d
Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability
The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...
EMBO Press7d
DNA methylation changes during acute COVID-19 are associated with long-term transcriptional dysregulation in patients’ airway epithelial cells
Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...
The Mirror14d
Gene Hackman's will reveals children are not included in bombshell new development
Actor Gene Hackman’s children are NOT included ... something like leaving everything to a caretaker." In a further development, Hackman’s estate are trying to block the Santa Fe medical ...
eLife16d
Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
The New York Times21d
A Haunting Coda: The 7 Days Gene Hackman’s Wife Could No Longer Care for Him
The exact details may never be known, but Mr. Hackman, 95 with advanced Alzheimer’s, was alone for about a week after his wife and sole caregiver died. By Nicholas Bogel-Burroughs Julia Jacobs ...
Frontiers22d
Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells
Future studies are needed to further elucidate the role of DEGS identified in this study in the development ... gene expression only for males and females. Any comparisons between age groups was ...
Frontiers25d
Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development
Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene ...