DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of ...

Pharmaceuticals announced that a new patent has been granted by the Japanese Patent Office, JPO, in January 2025. This patent ...

1) would probably lead to early embryonal or ... the potential to either inactivate the polymerase, or to form polymerase–DNA crosslinks. In the case of cancer treatment, an important strategy ...

1 Denaturation: Double-stranded DNA separates into single ... 6 A combination of highly processive thermostable DNA polymerase and a high-fidelity polymerase with 3′-5′ exonuclease activity helps ...

Scientists use short oligonucleotides as primers for polymerase chain reaction and next-generation sequencing, in DNA microarrays and fluorescence in situ hybridization, and in antisense therapies. (1 ...

Direct chemical synthesis has been adapted to make oligonucleotides of remarkable length, including an 800 nucleotide green ...

where the enzyme DNA polymerase zips along the single strands starting at the primer to replicate the DNA. The cycle repeats and copies of the original DNA accumulate exponentially. Like any ...