Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Based on this mutation, we constructed a new vector for the applications ... and incubated at 37°C in 5% CO 2. When BHK-21 cells are 80–90% confluent, they are ready for transfection. The plasmid was ...

The wild-type or inverted exon 4 and the flanking intronic sequences (250 bp) were cloned into the pET-01 vector using BamHI and NotI restriction enzyme sites. The plasmids were transfected into ...

AstraZeneca has entered the “off-the-shelf” cell therapy space, penning a $1 billion deal to acquire EsoBiotec and its ...

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

What Is B-Cell Lymphoma? B-cell lymphoma is a cancer that forms in your white blood cells called lymphocytes. These cells are made by your lymphatic system, which plays an important role in immunity.

Scientists have developed a new method that can grow motor neurons from skin cells, which may serve as a platform for ALS ...

Mechanistic studies reveal that HDAC6 overexpression disrupts mitotic spindle orientation and positioning in corneal epithelial cells. Our data further show that HDAC6 deacetylates enkurin ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...