For example, activation of a synthetic Notch (synNotch) receptor that binds one antigen can trigger the expression of a CAR targeting another antigen. 5 (4) A CAR controlled remotely via drugs and ...
(Top right) Antigen escape: tumor cells can downregulate or lose the expression of the targeted antigen, resulting in antigen escape, where CAR-T cells are no longer able to recognize and attack tumor ...
High-level PSMA expression is correlated with early PSA recurrence in surgically ... Thorek D, Abou D, Beattie B, Bartlett R, Huang R, Zanzonico P, Grimm J. “Positron Lymphography; Multimodal, ...