Let us help you with your inquiries, brochures and pricing requirements Request A Quote Download PDF Copy Download Brochure A therapeutic antibody’s efficacy is ...

Human IgG is a complex molecule composed of four protein chains with attached carbohydrates. A full-size IgG antibody is a Y-shaped ... whereas six bispecific Fab candidate fragments have been ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Two hinge regions link the Fab and Fc portions of each antibody molecule ... each with unique effector functions. Protein antigens typically elicit IgG1 and IgG3 responses, whereas IgG2 and ...

Immunotherapy. 2012;4(11):1167-1179. Up to half the patients on anti-TNF-α therapies have inadequate responses. Substantial inter- and even intra-individual variations in the pharmacokinetics of ...