A significant percentage of patients with RA and ANCA positivity were also diagnosed with AAV, with GPA being the most common subtype.

The dosing schedule of NKX019 was harmonized across all four clinical trials in the fourth quarter of 2024. Patients receive NKX019 on Days 0, 3 and 7 following single-agent lymphodepletion with ...

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) plays a significant pathogenic ... such as female predominance, little or no lung or kidney involvement, the presence of ...

cryoglobulinemic vasculitis, autoimmune hemolytic anemia, autoimmune lymphoproliferative syndrome or mixed connective tissue disease. * Alveolar hemorrhage requiring invasive pulmonary ventilation ...

Conduit Pharmaceuticals reports advancements in lupus studies and trial designs. The Company partnered with Charles River Laboratories to conduct preclinical studies of glucokinase inhibitors for ...

Diabetes-related kidney disease can worsen and lead to failure. You may experience many different symptoms, including lower back pain, fatigue, and nausea or vomiting. If you have kidney disease ...

Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials ...

Medscape Medical News, September 18, 2022 TCT 2022 Ultrasonic Renal Denervation Passes Key HTN Test: RADIANCE II No ill effects were seen in the sham-controlled trial of patients with uncontrolled ...

90.2% of patients with anti-AQP4 antibody-positive NMOSD were female, while 45.5 % of those with MOGAD and 66.7 % of those who were double seronegative were female. Patients with anti-aquaporin 4 ...