VDR 基因对于介导维生素 D 在免疫系统中的作用至关重要,由于错义突变导致其结构破坏,可能在很大程度上促成了白癜风的发病机制。错义单核苷酸多态性(SNPs)能够改变 VDR 蛋白的氨基酸序列 ...
Incyte is preparing to take an oral JAK inhibitor into phase 3 trials for the skin depigmentation disease vitiligo, after reporting mid-stage data showing efficacy in patients with facial and full ...
该成果揭示了一种以碱基修饰核苷酸为第二信使的细菌抗噬菌体(病毒)免疫信号通路,称之为“孔明系统”(Kongming),该机制通过“借用”噬菌体自身 ...