Conclusions Our study highlights the specific role of BMP/TGF-β and VEGF/VEGFR signalling in the aetiology of BAVM ... were injected into embryos at the 1-cell to 2-cell stage. Two morpholinos (one ...

After 4 days expression, CA1 pyramidal neurons were imaged in ACSF ... for homology-directed repair (HDR) were transfected into Neuro 2a cells by electroporation. Genomic DNA from the ...

In vitro, we compared the growth rates, neuronal differentiation and immunostaining of neuron markers in mouse neuroblastoma cell line (Neuro-2a) and primary culture of mouse trigeminal ganglion cells ...

Validcare CEO Patrick McCarthy said, “We are very excited to be working with Algernon Neuro on their upcoming, ground-breaking Phase 2a DMT stroke study and we are very pleased to become an ...

Validcare CEO Patrick McCarthy said, "We are very excited to be working with Algernon Neuro on their upcoming, ground-breaking Phase 2a DMT stroke study and we are very pleased to become an investor, ...

In agreement with neurite outgrowth results, a marker of neurite outgrowth (GAP-43 gene expression) was significantly increased in Neuro-2a cells treated with EGCG (10 μM), OFA (5, 10 μM), and OFB (5, ...

Tumor migration and invasion are a hallmark of most human cancers and remain a major source of treatment failure in patients with malignant tumors (1, 2). Nervous system tumors represent some of the ...

Using both okadaic acid treatment and RNA interference, we demonstrate that PP2A constitutively dephosphorylates the class IIa member HDAC7 to control its biological functions as a regulator of T cell ...