Unfortunately, there isn't an enzyme for many reactions we would sorely like to catalyze—things like digesting plastics or ...

AI-designed esmGFP protein could not have evolved naturally Scientists say esmGFP took 500M years’ worth of mutations to design AI-driven protein engineering could advance medicine and drug discovery ...

PROteolysis TArgeting Chimeras (PROTACs) are small molecules that induce target protein degradation via the ubiquitin-proteasome system. PROTACs recruit the target protein and E3 ligase; a critical ...

Apple’s first foldable iPhone is reportedly going to be a clamshell folding device ... A smaller model would unfold to a display size that would be larger than an iPhone 16 Pro Max, intended ...

Here we examine import of a model precursor protein derived from the ribonuclease barnase and show that mitochondria unfold this protein by unraveling it from its N-terminus. Because barnase in ...

fluorescent protein. Prior research has shown that synthesizing proteins can provide unique insights into the structure and function of natural proteins. To date, most such proteins are copies of ...

It’s usually done between weeks 11 and 14 of pregnancy. All unborn babies have a skin fold, called a nuchal fold, at the back of the neck that holds fluid. Babies with certain genetic ...

“At high temperatures, proteins will start to unfold and become inactive,” Medina said. “The unfolding happens because when the temperature increases, the energy of the water molecules will ...

Charge regulation can play a major role in the stabilization of protein structure. (18,23,24) Mechanistically, shifts in the charge state equilibrium may be attributed to differences in solvent ...

A NOVEL method for the fluorescent labelling of proteins has been described recently which involved treatment of a protein solution with an active labelling dye dispersed, on diatomaceous earth or ...

Structural and chemical instability of naked, nonmodified nucleic acids • Availability of conclusive biochemical or in vivo assays for protein activity • Design and selection • Complex folding ...

Figure 1. Structural representation of KcsA (PDB: 3EFF) and KirBac1.1 (PDB: 7SWJ) channels. For clarity, only two out of the four identical full-length subunits are shown for both channels. Each ...