The DCs in the synovium or circulation secrete IL-1, IL-6 and TNF-α. These cause systemic features of polymyalgia rheumatica. DC: Dendritic cell; TCR: T-cell receptor; TLR: Toll-like receptor.

Current Understanding and Management of Giant Cell Arteritis and Polymyalgia Rheumatica Parasar Ghosh; Frances A Borg; Bhaskar Dasgupta Disclosures Expert Rev Clin Immunol. 2010;6 (6):913-928. 0 ...

Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European ...

Polymyalgia rheumatica (PMR) is a chronic inflammatory disease of unknown aetiology affecting people aged over 50. The hallmark manifestations of PMR are pain and stiffness affecting the neck and ...