Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

Minor histocompatibility antigens selectively expressed on hematopoietic cells cause a graft-versus-leukemia effect, but not graft-versus-host disease; antigens expressed on hematopoietic cells ...

Background: the sophisticated cellular heterogeneity of cell populations in glioblastoma (GBM) has been a key factor influencing tumor progression and response to therapy. The lack of more precise ...

Hyperpigmentation usually involved the skin of the face or extremities, but 1 patient had pigmentation of the buccal mucosa that made the differentiation ... cells was considerably above the ...

1 University of Leeds Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK Background The human enthesis conventional T cells are poorly characterised. Objectives To study the biology ...

Significant technological progress has been made in identifying hematological stress inducers and treating hematopoietic diseases ... affecting the stem cell niche maintenance, self-renew, and ...

But now, researchers at UCSF are showing it's also happening in the lungs. They found hematopoietic stem cells (HSCs) in human lung tissue that make red blood cells, as well as megakaryocytes ...

While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent reports have questioned the physiological contribution ...

CD40 is a critical stimulatory receptor on antigen-presenting cells of the immune system. CD40-mediated activation of B cells is particularly important for normal humoral immune ... can promote B cell ...