Lupus in the modern era (1948-present) The sentinel event which heralded the modern era was the discovery of the LE cell by Hargraves and colleagues in 1948. The investigators observed these cells in ...

Stromal cell therapy is a promising frontier in lupus research, especially for people whose lupus doesn’t respond to other treatments (called refractory lupus). We were the first lupus organization in ...

Leukocytoclastic vasculitis (LCV), where neutrophils are predominant, and lymphocytic vasculitis, where lymphocytes are predominant, are inflammatory cells ... syndromes in LE (Lupus Foundation ...

Assistant Professor Andrew Monteith's lab in the Department of Microbiology is documenting how key immune cells detect ...

The transcription factor interferon regulatory factor 5 (IRF5) has previously been implicated in systemic lupus erythematosus (SLE) development, but its precise role in this process is unknown.

When researchers reintroduced AHR-activating molecules into the blood samples taken from those with lupus, the immune cells balanced out again. "We found that if we either activate the AHR pathway ...

The Lupus Research Alliance (LRA) is proud to announce the inaugural recipients of the new Targeted Research Program on ...

Long-lived plasma cells, which produce autoantibodies in diseases such as systemic lupus erythematosus (SLE), are an as yet unexplored therapeutic target in such antibody-mediated disorders.

NEW YORK, March 20, 2025 /PRNewswire/ -- The Lupus Research Alliance (LRA) is proud to announce the inaugural recipients of the new Targeted Research Program on Engineered Cell Therapies for Lupus ...