The researchers can identify infected mice that develop leukemia, isolate the white blood cells and ... in clinical samples from patients with AML and myelodysplastic syndromes.

More information: Rebekka Wegmann et al, Single-cell landscape of innate and acquired drug resistance in acute myeloid ...

In preclinical studies, these agents effectively block the function of MCL-1, reducing the ability of AML cells to survive. However, it has been found that ... "If one can identify those escape ...

"Relapse of AML after stem ... only the range of cell types in the bone marrow, but also how those cells were interacting and driving immune responses in the patient. The found that patients ...

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells. Its diversity stems from numerous genetic ...