eLife4d
The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity
To produce viruses (SYN1-GFP, LV-HSF1 [VectorBuilder], LV-ORF [VectorBuilder ... MS using a Dionex UltiMate 3000 Rapid Separation LC system coupled to a linear ion trap—Orbitrap hybrid Elite mass ...
eLife4d
Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
The Hatten lab NeuroD1-TRAP data was downloaded from GEO (GSE74400 ... Timed pregnant mothers homozygous for the Math1-GFP reporter were sacrificed using cervical dislocation following deep anesthesia ...
BMJ6d
Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis
Objective We aimed to understand the role of the transcriptional co-factor Yes-associated protein (Yap) in the molecular pathway underpinning the pathogenic transformation of synovial fibroblasts (SF) ...