Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

Moreover, each step in the flow of information from DNA ... made proteins also greatly influences protein levels. How Is Gene Expression Regulated? The amounts and types of mRNA molecules in ...

The research team developed a three-step computational pipeline applied to sections ... Statistical analysis: The mechanical ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene expression data, converts it into pathway activity matrices using eight ...

Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

Gene expression is not always an all-or-nothing ... and they do so at various steps in both transcription and translation. Nonetheless, each of these strategies begins at the level of DNA.

The first steps following gene discovery have become somewhat routine: completing sequencing of the gene, matching the sequence to a known protein pattern (if possible), deciphering gene expression ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

1 There are four key steps in the RNAi pathway ... 1 Scientists have harnessed RNAi in the laboratory to selectively silence target gene expression, a technique known as gene knockdown. 8 By ...