Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, ...

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Genetic engineering in non-human primates has historically faced limitations due to the reliance on virus-based gene delivery methods.

Researchers successfully use a nonviral, piggyBac transposon system to introduce a transgene into cynomolgus monkeys.

Researchers in Japan successfully used a nonviral system to introduce a transgene – that is, a gene that has been ...

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.

Zandy Forbes’ biotech company MeiraGTx has developed targeted gene therapy methods to treat more than just genetic disorders. Now it’s on the cusp of its first regulatory approval. Each year ...

The team was able to reach protein yields at the pool stage that couldn’t be achieved previously with a random integration approach.