Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

RNAi -- functions specifically to silence, or deactivate, genes. Among other applications, it promises to be groundbreaking ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Brain cells, or oligodendrocytes (green), in the hippocampus are marked with the GFP genetic marker in the mouse brain. These cells often deteriorate ...

Time-lapse confocal live imaging of 8-week K14:H2B-GFP murine MG explant in which all ... Stratton Professor of Gene and Cell Medicine, Director of the Institute for Regenerative Medicine, and ...

Using this gene delivery method, the scientists introduced the marker GFP into the neurons of a ... Adeno-associated viruses ...

Autophagy was quantified by western blotting of LC3, transmission electron microscopy analyses and confocal microscopy scanning of mRFP-GFP-LC3 reporter construct ... Results The expression of miR-541 ...

Higher levels and co-expression of WAVE2 and ARP2 have also been found in human ... were purchased from Abcam (Cambridge, United Kingdom). Anti-GFP (sc-9996) was purchased from Santa Cruz ...