When UV radiation damages messenger RNA (mRNA), it triggers a response in ribosomes (protein-building structures in cells), a process controlled by a protein called ZAK-alpha, which acts as an ...

One-cell-stage zebrafish embryos were injected with 1-2 nL of capped eGFP-nanos3’UTR mRNA using a pico-liter injector (Warner Instruments, PLI90A) and needles pulled from glass capillary tubing ...

The study protocol was approved by the Veterans Affairs Medical Center's research and development committee. There was no direct contact with human subjects in this study, therefore the hospital's ...

there are technologies available to help analyze the complex LNP systems used in delivering mRNA, such as the ultra-high-performance liquid chromatography-charged aerosol detector (UHPLC-CAD ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Clustered regularly interspaced short ...

[Effect of geniposide on LPS-induced activation of TLR4-NF-κB pathway in RAW264.7 macrophage cell line].

The effects of mTOR inhibition on CDT have been well-studied in various cancer models, and these studies have revealed that alterations to mTOR signaling affect the translation of specific subsets of ...

The global pandemic has not only changed our plans for how we live and work, but also accelerated the need for innovation to protect human health. Join us for an Innovation Summit to hear firsthand ...