The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Our blood consists of many cell types that develop through different stages from a precursor type – the blood stem cell. An ...

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

Ten years of substantial work by Nathalie Labrecque's team at the Montreal Clinical Research Institute (IRCM) and the ...

CD34 and CD45 expression were analyzed via flow cytometry ... DLL4 and VCAM1 were used as a supportive environment to drive differentiation to NK cell lineage. Image Credit: ACROBiosystems Figure ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative ...

Bone morphogenetic proteins (BMPs) directly affect the osteogenic differentiation of stem cells and are integral to bone ...