A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

Janet Mertz’s work with simian virus 40 DNA during her graduate years was pivotal for developing DNA recombination as we now know it. In September 1970, Janet Mertz joined the biochemistry department ...

circular DNA molecules. Plasmids are used in molecular biology to build gene circuits because they are easy to modify and can boost gene expression. However, plasmid copy numbers can fluctuate ...

In step 2, the gene fragment is integrated into a circular piece of DNA, called a plasmid, which is the main delivery vehicle into the cell and contains an antibiotic resistance gene for plasmid ...

Bacteria commonly produce toxins that are lethal to themselves, but also produce the required antitoxins. These toxin-antitoxin (TA) systems may be useful in modifying bacteria for biotechnology ...

A new study in the journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are ...

The South Korean biotech says the DNA plasmid-based therapy has been administered to a patient at Innovative Research of West Florida. The aim is to enrol 152 DPN patients at 15 clinical sites ...

Zydus Cadila has filed for emergency use approval (EUA) in India of its plasmid DNA-based vaccine for COVID-19, which if given a green light could become the first shot of its type to be cleared ...