X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in ...

X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in T-cell, B-cell, and natural ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

To establish stable cell lines, MDA-MB-231 and MCF-7 cells were transfected with an expression vector encoding VIPR2-EGFP or a control EGFP vector and cultured in the presence of 1 mg/ml G418 (Nacalai ...

Female nude mice (BALB/c, 4-6 weeks old) were obtained from Shanghai SLAC Laboratory Animal Co., Ltd. A total of 2 × 10 6 NCI-H1299 cells transfected with shPDE1A/control shRNA or PDE1A overexpressing ...

Based on this mutation, we constructed a new vector for the applications ... and incubated at 37°C in 5% CO 2. When BHK-21 cells are 80–90% confluent, they are ready for transfection. The plasmid was ...

AstraZeneca has entered the “off-the-shelf” cell therapy space, penning a $1 billion deal to acquire EsoBiotec and its ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... Feb. 4, 2025 — Researchers have ...

You, me, and all of the 108 billion or so Homo sapiens who’ve ever walked the Earth have all been our own constellation of some 30 trillion cells. Each of our bodies is a collective organism of ...

Mar. 19, 2025 — The cells that make up the walls of the finest of all lymphatic vessels have a lobate, oak leaf-like shape that makes them particularly resilient to changes in fluid volume.