This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

With the theoretical part extended, this paper would be of interest to cell biologists and biophysicists working on asymmetric partitioning during cell division. Asymmetric partition of fate ...

Ratings for Lineage Cell Therapeutics LCTX were provided by 7 analysts in the past three months, showcasing a mix of bullish and bearish perspectives. The table below provides a snapshot of their ...

Reduced commitment into the B-cell lineage is not due to an intrinsic haematopoietic stem cell defect, but likely to a non-permissive bone marrow niche in AAV. Low BAFF-receptor expression on B cells ...

In turn, MEIS TFs promote the accumulation of the methyltransferase KMT2D to initiate lineage-specific enhancer commissioning. MEIS combinatorial binding dynamics, dictated by the changing dosage of ...

When your doctor talks to you about your B-cell lymphoma, they'll tell you what type you have. It's an important piece of info to get, because each type of this cancer acts differently and has its ...

Lineage, Inc. emphasized its strong operational performance, backed by innovation and strategic capital deployment, while navigating a challenging market environment. The LinOS system and state-of ...

With differentiated pharmacokinetics compared with other approved BTK inhibitors, BRUKINSA has been demonstrated to inhibit the proliferation of malignant B cells within a number of disease ...