Researchers have shed new light on how tissues in the body are repaired following the damage and premature death of tissue ...

Our bodies naturally age as cells gradually become less active, transitioning into a state known as senescence. Senescent cells are not just older; they are distinctly larger and characterized by ...

E Measurement of Aβ40 secreted from HEK293T cells expressing β-CTF treatment with vehicle or PF. n=4. F-G Representative images and spine density of basal dendrites from CA1 pyramidal neurons ...

Colorectal tumors harbor increased levels of phosphorylated eIF2α. Disrupting the eIF2Bα homodimer is detrimental for CRC cells. The ability to sense eIF2α phosphorylation is essential for CRC cell ...

This requires the ability to accurately track cells, observing their function, movement and interactions in vitro and in vivo. GFP ioMicroglia is built from the company’s well-established ioMicroglia.

Suppressing a transcription factor induced energy burning in fat cells, offering therapeutic targets to treat obesity and metabolic diseases. When the researchers monitored the metabolic rates of the ...

HEK-293T cells were maintained in Dulbecco’s modified Eagle ... and maintained in RPMI-1640 medium. Luciferase/GFP-expressing cell lines (BGC-823-GL and KATO-III-GL) were generated by transfection of ...

contrary to the WT Fam65b-GFP protein. We next used this mutant to determine to what extent Fam65b phosphorylation impacts on its ability to bind RhoA. For this purpose, plasmid constructs encoding ...