Robert F. Kennedy's nomination will put Republican lawmakers' loyalty to the test, as the former Democrat holds a range of unorthodox positions that could alienate both conservatives and liberals.

As Robert F. Kennedy Jr. faced skeptical senators Thursday in the second day of his confirmation hearing to lead the department of Health and Human Services, Sen. Bill Cassidy confronted Kennedy about vaccines.

Sen. Bill Cassidy, the top Republican on the Senate Committee on Health, Education, Labor and Pensions, concluded Thursday's hearing by saying he was "struggling" with the nomination due to Kennedy's vaccine positions. Kennedy notably refused to say vaccines don't cause autism as he faced pointed question from lawmakers.

Vaccination bills are popping up in more than 15 states as lawmakers aim to potentially resurrect or create new religious exemptions from immunization mandates, establish state-level vaccine injury databases or dictate what providers must tell patients about the shots.

Robert F. Kennedy Jr. transferred ownership of the trademark application in December and its abbreviation — MAHA — to an LLC managed by Del Bigtree.

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The hearings were packed to capacity with protesters and fans, while the spillover crowd hung out in hallways and overflow rooms.

WASHINGTON (AP) — Robert F. Kennedy Jr.’s anti-vaccine advocacy is outside the mainstream. His previous statements on abortion could alienate Republicans. But a new poll finds that not all of his controversial health goals are unpopular — in fact, at least one has broad support among Democrats and Republicans.

That drew quick pushback from Democratic Sen. Ron Wyden of Oregon — and ensuing back and forth between him and Kennedy. Wyden pointed out the health secretary nominee has previously claimed there's “no safe” vaccine. Wyden also quoted from Kennedy's books, which say that parents have been “misled” on the measles vaccine.

The Texas legislature is debating bills that advocates say could give individuals more choice in whether they vaccinate themselves and their children.

Robert F. Kennedy Jr. is distancing himself from his anti-vaccine work as he seeks to become the leader of the nation’s top health agency under President Donald Trump, according to government ethics documents released on Wednesday.

Kennedy's confirmation is in the hands of a few Senate Republicans, some of whom have expressed concerns about his views on vaccines.