A personalized tumor ... DNA samples were sequenced to identify tumor-specific mutations in 155 cancer-associated genes. Top personalized mutations with the highest ranking scores were used to detect ...

Use of a standardized cell-free (cf)DNA-sequencing and cancer-screening ... Of the 20 participants with solid tumors, two had stage I disease, five had stage II or III disease, and 13 had stage ...

Kokoris came up with the idea of solving some of the noise issue of nanopore sequencing by converting DNA into larger surrogate polymers, and he cofounded sequencing company Stratos Genomics back in ...

"For solid tumors—the major killers in cancer—there ... refers to chemical modifications to the genome that don't change the DNA sequence. If DNA is a cell's hardware, the epigenome is the ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Alan Tan explores circulating tumor DNA, its role in clinical trials and its potential ... We don't necessarily need to wait until the cancer comes back at a solid tumor, radiographic progression,” he ...

from early detection of colorectal cancer to deep tumor characterization using cell free DNA. In short, the era of DNA sequencing that began with the human genome project may be coming to an end. But ...

However, traditional CAR T cell therapy has had limited success in solid tumors. Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector ...

Optimal therapeutic targeting of cancer involves clonal signals which are expressed within all cancer cellsGradalis applies a novel clinically ...

DNA sequencing can uncover the complex genetic and epigenetic factors that cause aggressive paediatric cancers and their recurrence.