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The San Francisco 49ers' disappointing season continued on "Monday Night Football" against the Detroit Lions. At first, things looked good for the 49ers as they took a 21-13 lead into halftime.

Don’t try to tell John Lynch the San Francisco 49ers should be happy about boosting their draft positioning by losing a meaningless game. This week’s Monday Night Football game was meaningless ...

The Detroit Lions and San Francisco 49ers reprised their NFC Championship game with a rematch on Monday Night Football. While the Lions were still fighting for the No. 1 seed in the NFC playoffs ...

The final Monday Night Football game of the 2024 season ... For the Detroit Lions — who defeated the San Francisco 49ers 40-34 — Week 18’s game against the Minnesota Vikings will decide ...

The San Francisco 49ers are playing for pride on Monday Night Football when they host the Detroit Lions. Can Brock Purdy and the 49ers salvage a disastrous season with a mental victory on MNF? Matt ...

The San Francisco 49ers will miss another key player on Monday Night Football. San Francisco won't get a chance to defend its NFC title after getting eliminated from playoff contention in Week 16.

The Detroit Lions are 3.5-point favorites over the San Francisco 49ers in the final Monday Night Football contest of the 2024-25 NFL season. The Lions can clinch the top seed with a victory and a ...

The Detroit Lions are expected to play their starters on Monday Night Football against the San Francisco 49ers, despite the game being a dud. The result is essentially meaningless. "We’re going ...

The Detroit Lions might very well be the best team in the NFL. Yet with only two games left to play in the regular season, they haven't even wrapped up their own division. Coming into Week 17, the ...