Fluorescent proteins are also useful for tracking cell populations, such as tumor cells, in vivo. Thus far, the best tools for imaging in live, whole animals have been far-red fluorescent proteins ...

For a time, however, it appeared that fluorescent protein engineering had hit a 'yellow' wall in efforts to red-shift fluorescence emission. Fortuitously, this barrier had already been surmounted ...

The researchers injected lung-targeted SORT LNPs intravenously to healthy mice engineered to express a red fluorescent protein in any cell that underwent gene editing. When Siegwart’s team isolated ...

AI-designed esmGFP protein, structurally unique from natural proteins, could speed up advancements in biotechnology.

Researchers have recently identified the protein benzyl alcohol O-benzoyltransferase ... marker called mVenus and comparing it with a red fluorescent marker for peroxisomes (mCherry-PTS1).

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

That's the equivalent of 500 million years of evolution being processed by AI, the research team estimates, and it opens the way to creating custom-made proteins that can be designed for specific uses ...

Guided by a multimodal generative language model called ESM3, Thomas Hayes and colleagues generated and synthesized a previously unknown bright fluorescent protein, with a genetic sequence so ...

1 This was the first example of a light-activated protein, which they called a photoprotein. I wanted to have a tool like this. I thought this would be wonderful. —Martin Chalfie, Columbia University ...

fluorescent protein. Prior research has shown that synthesizing proteins can provide unique insights into the structure and function of natural proteins. To date, most such proteins are copies of ...