In the treatment of psoriasis, preliminary evidence supports the hypothesis that IL-23 inhibitors are capable of extended ...

While IL-12 goes on to enhance production of Th1 cells (which also drives keratinocyte activation in psoriasis through TNF-α and INF-γ production), IL-23, composed of IL-23p19 and IL-12p40 ...

The company is currently focused on a number of different therapeutic areas, including diabetic foot ulcers, multiple sclerosis, and psoriasis ... of fibroblasts, keratinocyte migration, and ...

Adults and adolescents treated with icotrokinra experienced improvements in their moderate to severe plaque psoriasis. “Its mechanism of action is fairly unique in dermatology,” Bissonnette ...

Psoriasis is one of the most common chronic ... The researchers have now decoded the exact mechanism behind this for the first time: "We were able to show that the loss of the anti-inflammatory ...