and dysregulation of keratinocyte growth 2. Despite the availability of a variety of treatment options for psoriasis and psoriatic arthritis, both patients and health-care providers continue to ...

In the treatment of psoriasis, preliminary evidence supports the hypothesis that IL-23 inhibitors are capable of extended ...

While IL-12 goes on to enhance production of Th1 cells (which also drives keratinocyte activation in psoriasis through TNF-α and INF-γ production), IL-23, composed of IL-23p19 and IL-12p40 ...

Adults and adolescents treated with icotrokinra experienced improvements in their moderate to severe plaque psoriasis, ...