Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

When mice are full and eat sugar, these nerve cells not only release signaling molecules that ... to eat sugar even beyond fullness. This opioid pathway in the brain was specifically activated ...

In mice and humans, the "dessert-stomach pathway" is activated by mere perception by releasing the opiate ß-endorphin, which makes evolutionary sense because sugar provides quick energy. Blocking ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

Blocking opiate signaling in this pathway could support current and future obesity treatments. Why do we crave sugary snacks on full stomach? To find out more about the brain's unique mechanism ...

Researchers from Tokyo University of Science uncover cellular and molecular mechanisms underlying the antidepressant-like effects of the delta opioid receptor agonists, paving the way for its ...

3 In 2016, the Massachusetts Department of Industrial Accidents (DIA), which administers the Massachusetts workers’ compensation program, initiated the Opioid Alternative Treatment Pathway (OATP) (ppt ...

Venetia Zachariou, PhD, Edward Avedisian Professor and chair of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, has received a Distinguished ...

as a non-opioid treatment for moderate to severe acute pain in adults. Journavx's main ingredient works by targeting a pain-signaling pathway that involves sodium channels in the peripheral ...