When mice are full and eat sugar, these nerve cells not only release signaling molecules that ... to eat sugar even beyond fullness. This opioid pathway in the brain was specifically activated ...

Blocking opiate signaling of this pathway may support current and future obesity treatments. To find the cause of the "dessert stomach", the researchers investigated the reaction of mice to sugar ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

In mice and humans, the "dessert-stomach pathway" is activated by mere perception by releasing the opiate ß-endorphin, which makes evolutionary sense because sugar provides quick energy. Blocking ...

Researchers from Tokyo University of Science uncover cellular and molecular mechanisms underlying the antidepressant-like effects of the delta opioid receptor agonists, paving the way for its ...

Blocking opiate signaling in this pathway could support current and future obesity treatments. Why do we crave sugary snacks on full stomach? To find out more about the brain's unique mechanism ...

Venetia Zachariou, PhD, Edward Avedisian Professor and chair of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, has received a Distinguished ...

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway - with therapeutic potential. Atherosclerosis is the most common cause of life-threatening ...